P154L (p.Pro154Leu) variant of DLG4 (Disks large homolog 4)
P154L (p.Pro154Leu) in DLG4 (Disks large homolog 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P154L (p.Pro154Leu) variant details
- p.Pro154Leu
- ExAC rs779621148
- TOPMed rs779621148
- gnomAD rs779621148
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.08
- CADD 19.90
- PolyPhen-2 0.02
- SIFT 0.37
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available