K98N (p.Lys98Asn) variant of DLG4 (Disks large homolog 4)
K98N (p.Lys98Asn) in DLG4 (Disks large homolog 4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
K98N (p.Lys98Asn) variant details
- p.Lys98Asn
- NCI-TCGA Cosmic COSV5724
- cosmic curated COSV57240
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.20
- CADD 24.10
- PolyPhen-2 0.92
- SIFT 0.08
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available