I161L (p.Ile161Leu) variant of DLG4 (Disks large homolog 4)
I161L (p.Ile161Leu) in DLG4 (Disks large homolog 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data.
I161L (p.Ile161Leu) variant details
- p.Ile161Leu
- TOPMed rs2070270144
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.06
- CADD 21.10
- PolyPhen-2 0.30
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)