G197A (p.Gly197Ala) variant of DLG4 (Disks large homolog 4)
G197A (p.Gly197Ala) in DLG4 (Disks large homolog 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
G197A (p.Gly197Ala) variant details
- p.Gly197Ala
- TOPMed rs1344403587
- gnomAD rs1344403587
- Missense
- Variant Prioritization Score for Impact Estimate 0.607
- REVEL 0.48
- CADD 25.10
- PolyPhen-2 0.99
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available