G185R (p.Gly185Arg) variant of DLG4 (Disks large homolog 4)
G185R (p.Gly185Arg) in DLG4 (Disks large homolog 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
G185R (p.Gly185Arg) variant details
- p.Gly185Arg
- ExAC rs759632708
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- REVEL 0.53
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available