G169D (p.Gly169Asp) variant of DLG4 (Disks large homolog 4)
G169D (p.Gly169Asp) in DLG4 (Disks large homolog 4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
G169D (p.Gly169Asp) variant details
- p.Gly169Asp
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.511
- REVEL 0.33
- CADD 25.20
- PolyPhen-2 0.34
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available