D91N (p.Asp91Asn) variant of DLG4 (Disks large homolog 4)
D91N (p.Asp91Asn) in DLG4 (Disks large homolog 4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
D91N (p.Asp91Asn) variant details
- p.Asp91Asn
- NCI-TCGA Cosmic COSV5723
- cosmic curated COSV57238
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.534
- REVEL 0.35
- CADD 26.90
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available