A155V (p.Ala155Val) variant of DLG4 (Disks large homolog 4)
A155V (p.Ala155Val) in DLG4 (Disks large homolog 4) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes structural context.
A155V (p.Ala155Val) variant details
- p.Ala155Val
- rs2142885359
- ClinGen CA397719222
- ClinVar RCV001797458
- Ensembl rs2142885359
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- AlphaMissense 0.08
- MetaLR 0.05
- MetaSVM -1.09
- PolyPhen-2 0.30
- SIFT 0.17
- MutPred 0.47
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available