S46F (p.Ser46Phe) variant of DIP2B (Q9P265)
S46F (p.Ser46Phe) in DIP2B (Q9P265) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
S46F (p.Ser46Phe) variant details
- p.Ser46Phe
- TOPMed rs1937926749
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.14
- MetaLR 0.15
- MetaSVM -0.65
- CADD 24.90
- PolyPhen-2 0.58
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available