R21W (p.Arg21Trp) variant of DIP2B (Q9P265)
R21W (p.Arg21Trp) in DIP2B (Q9P265) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
R21W (p.Arg21Trp) variant details
- p.Arg21Trp
- TOPMed rs1957955547
- gnomAD rs1957955547
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.33
- MetaLR 0.30
- MetaSVM -0.51
- CADD 31.00
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available