R21L (p.Arg21Leu) variant of DIP2B (Q9P265)
R21L (p.Arg21Leu) in DIP2B (Q9P265) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
R21L (p.Arg21Leu) variant details
- p.Arg21Leu
- gnomAD 12-50505202-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.32
- MetaLR 0.31
- MetaSVM -0.51
- CADD 23.80
- PolyPhen-2 0.08
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available