E28G (p.Glu28Gly) variant of DIP2B (Q9P265)
E28G (p.Glu28Gly) in DIP2B (Q9P265) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
E28G (p.Glu28Gly) variant details
- p.Glu28Gly
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.372
- REVEL 0.21
- MetaLR 0.16
- MetaSVM -0.75
- CADD 32.00
- PolyPhen-2 0.53
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available