D35G (p.Asp35Gly) variant of DIP2B (Q9P265)
D35G (p.Asp35Gly) in DIP2B (Q9P265) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
D35G (p.Asp35Gly) variant details
- p.Asp35Gly
- rs1443278274
- NCI-TCGA Cosmic COSV9999
- 1000Genomes rs1443278274
- gnomAD rs1443278274
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- REVEL 0.40
- MetaLR 0.32
- MetaSVM -0.38
- CADD 28.00
- PolyPhen-2 0.99
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the 1KG:ACB population (allele frequency 0.0054)
- Structural context available