Y47F (p.Tyr47Phe) variant of DICER1 (Endoribonuclease Dicer)
Y47F (p.Tyr47Phe) in DICER1 (Endoribonuclease Dicer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
Y47F (p.Tyr47Phe) variant details
- p.Tyr47Phe
- Ensembl rs753790391
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.37
- CADD 26.70
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.1e-05)
- Structural context available