R245K (p.Arg245Lys) variant of DICER1 (Endoribonuclease Dicer)
R245K (p.Arg245Lys) in DICER1 (Endoribonuclease Dicer) is a missense change. Clinical records from ClinVar and UniProt describe it as likely pathogenic in the context of DICER1-related tumor predisposition. The record also includes structural context.
R245K (p.Arg245Lys) variant details
- p.Arg245Lys
- NCI-TCGA Cosmic COSV5862
- cosmic curated COSV58628
- Likely pathogenic
- DICER1-related tumor predisposition
- Missense
- ClinVar: Likely pathogenic (DICER1-related tumor predisposition)
- UniProt: Likely pathogenic
- Structural context available