L14M (p.Leu14Met) variant of DICER1 (Endoribonuclease Dicer)
L14M (p.Leu14Met) in DICER1 (Endoribonuclease Dicer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
L14M (p.Leu14Met) variant details
- p.Leu14Met
- ExAC rs779753946
- gnomAD rs779753946
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- REVEL 0.28
- CADD 26.10
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available