F72L (p.Phe72Leu) variant of DICER1 (Endoribonuclease Dicer)
F72L (p.Phe72Leu) in DICER1 (Endoribonuclease Dicer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
F72L (p.Phe72Leu) variant details
- p.Phe72Leu
- cosmic curated COSV10943
- Missense
- Variant Prioritization Score for Impact Estimate 0.61
- REVEL 0.57
- CADD 28.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available