P81S (p.Pro81Ser) variant of DEPDC5 (GATOR1 complex protein DEPDC5)
P81S (p.Pro81Ser) in DEPDC5 (GATOR1 complex protein DEPDC5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
P81S (p.Pro81Ser) variant details
- p.Pro81Ser
- gnomAD 22-31765022-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.626
- CADD 22.50
- PolyPhen-2 0.08
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available