G15A (p.Gly15Ala) variant of DEPDC5 (GATOR1 complex protein DEPDC5)
G15A (p.Gly15Ala) in DEPDC5 (GATOR1 complex protein DEPDC5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
G15A (p.Gly15Ala) variant details
- p.Gly15Ala
- ExAC rs777122777
- gnomAD rs777122777
- Missense
- Variant Prioritization Score for Impact Estimate 0.78
- CADD 26.60
- PolyPhen-2 0.91
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available