P141L (p.Pro141Leu) variant of DDX41 (Q9UJV9)
P141L (p.Pro141Leu) in DDX41 (Q9UJV9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
P141L (p.Pro141Leu) variant details
- p.Pro141Leu
- ExAC rs781486582
- gnomAD rs781486582
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.33
- CADD 25.30
- PolyPhen-2 0.38
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available