I142M (p.Ile142Met) variant of DDX41 (Q9UJV9)
I142M (p.Ile142Met) in DDX41 (Q9UJV9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
I142M (p.Ile142Met) variant details
- p.Ile142Met
- TOPMed rs1761207365
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.16
- CADD 19.80
- PolyPhen-2 0.03
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available