S74Y (p.Ser74Tyr) variant of DDX3X (ATP-dependent RNA helicase DDX3X)
S74Y (p.Ser74Tyr) in DDX3X (ATP-dependent RNA helicase DDX3X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
S74Y (p.Ser74Tyr) variant details
- p.Ser74Tyr
- Ensembl rs2147348711
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.07
- ESM-1b 1.00
- AlphaMissense 0.37
- CADD 22.40
- PolyPhen-2 0.46
- SIFT 0.26
- Most common in the South Asian population (allele frequency 1.8e-05)
- Structural context available