S58T (p.Ser58Thr) variant of DDX3X (ATP-dependent RNA helicase DDX3X)

Name: DDX3X S58T (p.Ser58Thr) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-10-09
License: https://catvariant.com/terms-of-use

S58T (p.Ser58Thr) in DDX3X (ATP-dependent RNA helicase DDX3X) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes structural context.

S58T (p.Ser58Thr) variant details

p.Ser58Thr
NCI-TCGA Cosmic COSV1013
cosmic curated COSV10130
Variant assessed as somatic; moderate impact.
Missense
Variant Prioritization Score for Impact Estimate 0.402
ESM-1b 0.34
AlphaMissense 0.07
UniProt: Variant assessed as somatic; moderate impact.
Structural context available