S34G (p.Ser34Gly) variant of DDX3X (ATP-dependent RNA helicase DDX3X)
S34G (p.Ser34Gly) in DDX3X (ATP-dependent RNA helicase DDX3X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
S34G (p.Ser34Gly) variant details
- p.Ser34Gly
- gnomAD X-41337462-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.15
- ESM-1b 0.00
- AlphaMissense 0.06
- CADD 21.90
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available