R37H (p.Arg37His) variant of DDX3X (ATP-dependent RNA helicase DDX3X)
R37H (p.Arg37His) in DDX3X (ATP-dependent RNA helicase DDX3X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
R37H (p.Arg37His) variant details
- p.Arg37His
- gnomAD X-41339042-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.467
- REVEL 0.22
- ESM-1b 1.00
- AlphaMissense 0.58
- CADD 24.50
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the REMAINING population (allele frequency 2.6e-05)
- Structural context available
- Literature evidence available