P41T (p.Pro41Thr) variant of DDX3X (ATP-dependent RNA helicase DDX3X)
P41T (p.Pro41Thr) in DDX3X (ATP-dependent RNA helicase DDX3X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
P41T (p.Pro41Thr) variant details
- p.Pro41Thr
- gnomAD X-41339053-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.56
- REVEL 0.38
- ESM-1b 1.00
- AlphaMissense 1.00
- CADD 24.00
- PolyPhen-2 0.03
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.8e-05)
- Structural context available
- Literature evidence available