N22S (p.Asn22Ser) variant of DDX3X (ATP-dependent RNA helicase DDX3X)
N22S (p.Asn22Ser) in DDX3X (ATP-dependent RNA helicase DDX3X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
N22S (p.Asn22Ser) variant details
- p.Asn22Ser
- TOPMed rs1309663175
- gnomAD rs1309663175
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.08
- ESM-1b 1.00
- AlphaMissense 0.07
- CADD 23.00
- PolyPhen-2 0.04
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 3.3e-05)
- Structural context available