L21P (p.Leu21Pro) variant of DDX3X (ATP-dependent RNA helicase DDX3X)
L21P (p.Leu21Pro) in DDX3X (ATP-dependent RNA helicase DDX3X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
L21P (p.Leu21Pro) variant details
- p.Leu21Pro
- gnomAD X-41337424-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.625
- REVEL 0.57
- ESM-1b 1.00
- AlphaMissense 0.81
- CADD 32.00
- PolyPhen-2 0.69
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available