K66R (p.Lys66Arg) variant of DDX3X (ATP-dependent RNA helicase DDX3X)
K66R (p.Lys66Arg) in DDX3X (ATP-dependent RNA helicase DDX3X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
K66R (p.Lys66Arg) variant details
- p.Lys66Arg
- gnomAD rs1453386913
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.04
- ESM-1b 0.00
- AlphaMissense 0.07
- CADD 22.40
- PolyPhen-2 0.05
- SIFT 0.68
- Most common in the South Asian population (allele frequency 3.7e-05)
- Structural context available