G29E (p.Gly29Glu) variant of DDX3X (ATP-dependent RNA helicase DDX3X)
G29E (p.Gly29Glu) in DDX3X (ATP-dependent RNA helicase DDX3X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
G29E (p.Gly29Glu) variant details
- p.Gly29Glu
- gnomAD X-41337448-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.05
- ESM-1b 1.00
- AlphaMissense 0.16
- CADD 24.90
- PolyPhen-2 0.18
- SIFT 0.03
- Most common in the East Asian population (allele frequency 3.3e-05)
- Structural context available
- Literature evidence available