Y70H (p.Tyr70His) variant of DCX (O43602)
Y70H (p.Tyr70His) in DCX (O43602) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
Y70H (p.Tyr70His) variant details
- p.Tyr70His
- gnomAD X-111410191-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.585
- CADD 27.00
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- Literature evidence available