Y64D (p.Tyr64Asp) variant of DCX (O43602)
Y64D (p.Tyr64Asp) in DCX (O43602) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as pathogenic in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes structural context.
Y64D (p.Tyr64Asp) variant details
- p.Tyr64Asp
- rs1556405129
- ClinGen CA414246918
- ClinVar RCV003685084
- Pathogenic
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.754
- AlphaMissense 0.99
- MetaLR 0.83
- MetaSVM 0.82
- SIFT 0.05
- EVE 0.47
- ClinVar: Pathogenic (not provided)
- EBI: Pathogenic
- UniProt: Pathogenic
- Structural context available