Y64C (p.Tyr64Cys) variant of DCX (O43602)
Y64C (p.Tyr64Cys) in DCX (O43602) is a missense change. Clinical records from EBI and UniProt describe it as likely pathogenic. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes structural context.
Y64C (p.Tyr64Cys) variant details
- p.Tyr64Cys
- rs587783530
- ClinGen CA171878
- ClinVar RCV000145818
- Ensembl rs587783530
- Likely pathogenic
- Missense
- Variant Prioritization Score for Impact Estimate 0.817
- AlphaMissense 0.98
- MetaLR 0.91
- MetaSVM 1.04
- SIFT 0.00
- EVE 0.52
- EBI: Likely pathogenic
- UniProt: Likely pathogenic
- Structural context available