T88M (p.Thr88Met) variant of DCX (O43602)
T88M (p.Thr88Met) in DCX (O43602) is a missense change. Clinical records from ClinVar and UniProt describe it as conflicting interpretations in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.95 / 1. The record also includes structural context.
T88M (p.Thr88Met) variant details
- p.Thr88Met
- rs2147276286
- ClinGen CA414246762
- ClinVar RCV003129346
- NCI-TCGA Cosmic COSV5757
- Conflicting interpretations
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.951
- AlphaMissense 1.00
- MetaLR 0.95
- MetaSVM 1.10
- SIFT 0.00
- EVE 0.91
- ClinVar: Conflicting classifications of pathogenicity (not provided)
- UniProt: Conflicting interpretations
- Structural context available