S15F (p.Ser15Phe) variant of DCX (O43602)
S15F (p.Ser15Phe) in DCX (O43602) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
S15F (p.Ser15Phe) variant details
- p.Ser15Phe
- NCI-TCGA Cosmic COSV1005
- cosmic curated COSV10057
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.663
- CADD 22.80
- PolyPhen-2 0.17
- SIFT 0.13
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available