R16W (p.Arg16Trp) variant of DCX (O43602)
R16W (p.Arg16Trp) in DCX (O43602) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
R16W (p.Arg16Trp) variant details
- p.Arg16Trp
- gnomAD X-111410353-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- CADD 28.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available