V69D (p.Val69Asp) variant of DCC (Netrin receptor DCC)
V69D (p.Val69Asp) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
V69D (p.Val69Asp) variant details
- p.Val69Asp
- TOPMed rs1326511847
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.09
- MetaLR 0.01
- MetaSVM -0.94
- CADD 22.50
- PolyPhen-2 0.22
- SIFT 0.09
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available