V10A (p.Val10Ala) variant of DCC (Netrin receptor DCC)
V10A (p.Val10Ala) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
V10A (p.Val10Ala) variant details
- p.Val10Ala
- 1000Genomes rs192846998
- ExAC rs192846998
- gnomAD rs192846998
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.11
- MetaLR 0.06
- MetaSVM -1.04
- CADD 22.50
- PolyPhen-2 0.07
- SIFT 0.08
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available