T51A (p.Thr51Ala) variant of DCC (Netrin receptor DCC)
T51A (p.Thr51Ala) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
T51A (p.Thr51Ala) variant details
- p.Thr51Ala
- cosmic curated COSV10589
- 1000Genomes rs190581937
- ExAC rs190581937
- TOPMed rs190581937
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.17
- CADD 15.20
- PolyPhen-2 0.07
- SIFT 0.15
- Most common in the HGDP:TUJIA population (allele frequency 0.1)
- Structural context available