T38K (p.Thr38Lys) variant of DCC (Netrin receptor DCC)
T38K (p.Thr38Lys) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
T38K (p.Thr38Lys) variant details
- p.Thr38Lys
- cosmic curated COSV10049
- TOPMed rs1040684774
- gnomAD rs1040684774
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.17
- CADD 23.30
- PolyPhen-2 0.21
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available