S4I (p.Ser4Ile) variant of DCC (Netrin receptor DCC)
S4I (p.Ser4Ile) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
S4I (p.Ser4Ile) variant details
- p.Ser4Ile
- gnomAD 18-52340798-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.467
- REVEL 0.32
- MetaLR 0.16
- MetaSVM -0.75
- CADD 24.80
- PolyPhen-2 0.94
- SIFT 0.31
- Population evidence available
- Structural context available
- Literature evidence available