R67Q (p.Arg67Gln) variant of DCC (Netrin receptor DCC)
R67Q (p.Arg67Gln) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R67Q (p.Arg67Gln) variant details
- p.Arg67Gln
- cosmic curated COSV10049
- ESP rs146575994
- ExAC rs146575994
- gnomAD rs146575994
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.06
- CADD 17.70
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available