R53P (p.Arg53Pro) variant of DCC (Netrin receptor DCC)
R53P (p.Arg53Pro) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
R53P (p.Arg53Pro) variant details
- p.Arg53Pro
- ExAC rs768831554
- TOPMed rs768831554
- gnomAD rs768831554
- Missense
- Variant Prioritization Score for Impact Estimate 0.476
- REVEL 0.24
- CADD 27.40
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available