R41L (p.Arg41Leu) variant of DCC (Netrin receptor DCC)
R41L (p.Arg41Leu) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
R41L (p.Arg41Leu) variant details
- p.Arg41Leu
- cosmic curated COSV59123
- ExAC rs202005334
- TOPMed rs202005334
- gnomAD rs202005334
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.24
- CADD 3.57
- PolyPhen-2 0.11
- SIFT 0.49
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available