P11L (p.Pro11Leu) variant of DCC (Netrin receptor DCC)
P11L (p.Pro11Leu) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
P11L (p.Pro11Leu) variant details
- p.Pro11Leu
- gnomAD 18-52340819-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.17
- MetaLR 0.16
- MetaSVM -0.83
- CADD 24.60
- PolyPhen-2 0.98
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available