P11H (p.Pro11His) variant of DCC (Netrin receptor DCC)
P11H (p.Pro11His) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
P11H (p.Pro11His) variant details
- p.Pro11His
- TOPMed rs1297820968
- gnomAD rs1297820968
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.19
- MetaLR 0.16
- MetaSVM -0.79
- CADD 24.30
- PolyPhen-2 0.99
- SIFT 0.07
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available