L59I (p.Leu59Ile) variant of DCC (Netrin receptor DCC)
L59I (p.Leu59Ile) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L59I (p.Leu59Ile) variant details
- p.Leu59Ile
- ExAC rs762319358
- TOPMed rs762319358
- gnomAD rs762319358
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.18
- CADD 23.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available