L13V (p.Leu13Val) variant of DCC (Netrin receptor DCC)
L13V (p.Leu13Val) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
L13V (p.Leu13Val) variant details
- p.Leu13Val
- ESP rs373864086
- ExAC rs373864086
- TOPMed rs373864086
- gnomAD rs373864086
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.18
- MetaLR 0.14
- MetaSVM -0.97
- CADD 25.00
- PolyPhen-2 0.90
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available