K76E (p.Lys76Glu) variant of DCC (Netrin receptor DCC)
K76E (p.Lys76Glu) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
K76E (p.Lys76Glu) variant details
- p.Lys76Glu
- gnomAD 18-52752188-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.597
- REVEL 0.66
- MetaLR 0.20
- MetaSVM -0.57
- CADD 27.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available