K75R (p.Lys75Arg) variant of DCC (Netrin receptor DCC)
K75R (p.Lys75Arg) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
K75R (p.Lys75Arg) variant details
- p.Lys75Arg
- gnomAD 18-52752186-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.03
- MetaLR 0.02
- MetaSVM -0.99
- CADD 16.60
- PolyPhen-2 0.11
- SIFT 0.73
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available
- Literature evidence available